Metastatic melanoma has a high mortality rate that is associated with lymphatic progression of the disease. Currently available treatments fail to achieve therapeutic concentrations throughout the lymphatic system. This nanocarrier drug delivery platform is configured for selective uptake by lymph nodes and dissemination throughout the lymphatic system, providing therapeutic efficacy at lymph nodes both proximal and distal to the site of administration.
Catalytically converting organic species into fuels or valuable feedstocks typically requires devices that are not commercially scalable due to cost, operational and yield restrictions. This bioreactor device uses microchannel technology combined with biolamina substrates modified with biologically active materials. This architecture overcomes mass transfer and diffusion limitations, making the process highly scalable by increasing the number of biolamina reactors.
Most of today’s computers and devices use a Chip Multi-Processor (CMP) with a Network-on-Chip (NoC) architecture for communicating among the cores. Current NoC designs choose flexibility over efficiency, using routers that have high costs in chip area and power use. This new NoC technology offers the simplicity of a bus-based system and the speed of a router-based system. It incorporates a layered network to connect a series of cores with minimal distance.
Ideal bioorthogonal ligation is a method of controlling protein deposition and orientation on surfaces. Oregon State researchers are working to identify how this technology can meet current market needs for protein materials including carbon dioxide sequestering, the creation of protein sensors for better antibody drugs and metabolite sensors for athletes and doctors.